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Trimethoprim/sulfamethoxazole may be abbreviated as SXT, TMP-SMX, TMP-SMZ, or TMP-sulfa.

Sulfamethoxazole, a sulfonamide, induces its therapeutic effects by interfering with the de novo (that is, from within the cell) synthesis of folate inside microbial organisms such as protozoa, fungi and bacteria.

Immediately preceding text appears at serial pages (308921) to (308922). ‘‘ Statement’’ means a person’s oral assertion, written assertion, or nonverbal conduct, if the person intended it as an assertion. ‘‘ Declarant’’ means the person who made the statement. ‘‘ Hearsay’’ means a statement that (1) the declarant does not make while testifying at the current trial or hearing; and (2) a party offers in evidence to prove the truth of the matter asserted in the statement.

801(d)(1) (A Declarant-Witness’s Prior Statement) are covered in Pa.

Co-trimoxazole in retinochoroiditis shows a reduction in the risk of recurrent retinochoroiditis.

Despite this, its use during the first trimester (during organogenesis) and 12 weeks prior to pregnancy has been associated with an increased risk of congenital malformations, especially malformations associated with maternal folic acid deficiency (which is most likely related to the mechanism of action of co-trimoxazole) such as neural tube defects such as spina bifida, cardiovascular malformations (e.g.

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Absence of a Record of a Regularly Conducted Activity (Not Adopted).

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